I study mitochondrial DNA maintenance (replication and repair) in mammalian cells, concentrating on the tissue-specificity of molecular mechanisms and adaptative reactions to mitogenotoxic stressors.

Projects

A novel 18F-fluorine labeled tracer for imaging mitochondrial membrane potential based on fluorescent probe of JC-1

Relationship of vascular adhension protein-1(VAP-1) and cardiovascular factors

Evaluation of ammonia metabolism following carotid endarterectomy by PET imaging in human subjects

Dynamic study on 18F-FDG uptake after oral administration

I am working on iPSCs to study the impact of mitochondrial mutations. The mutations are known to cause neuro degenerative disorders like ALS.