Research projects 100

Vascular adhesion protein-1 (VAP-1) is an adhesion molecule and involved in leukocyte rolling, adhesion, and transmigration from the blood into sites of inflammation, which is important for the pathogenesis of atherosclerosis. VAP-1 was found and identified in Turku by Prof. Sirpa Jalkanen. In this study, we planed to investigate the relationship soluble VAP-1(sVAP-1) in serum with cardiovascular factors based on Chinese population. This is an internation collaboration project. Finland provides technical supports and VAP-1 antibodies to China. Parters in China performed population study.

Team

Dawei Chen, Jianchang Wang, Sirpa Jalkanen, Anne Roivainen, Juhani Knuuti

  • Head of research Juhani Knuuti
  • Language n/a

The purpose of research is to develop and validate a novel system for quantitative assessment of multi-organ tissue-perfusion using a dedicated cyclotron-produced, short-lived nuclei of 15O and PET for non-invasive human and small animal studies. This system is to overcome organ-specific problems. The goal is to establish a standard package for quantitative assessment of tissue perfusion, involving ICT-based multi-modality image processing techniques.

Team

(Board)Hidehiro Iida (iida@ri.vcvc.go.jp), Pirjo Nuutila, Mika Teräs, Nobuyuki Kudomi, (Main team members)Kazuhiro Koshino, Junichiro Enmi,Takashi Temma, Jarmo Teuho, Hannu Sipilä, Harri Merisaari, Marco Bucci, Kirsi Virtanen

Mitochondria,as "energy factories", are responsible for creating more than 90% of the energy needed by the body to sustain life. Mitochondrial disease is a group of disorders cuased by dysfunctional mitochondria. About 1 in 4,000 children will develope this disease by the age of 10 years.Currently there is no specific method to detect this disorder clinically. This study is designated to develop a novel PET tracer for imaging mitochondrial membrane potential (MMP), which is a key inditor for moniting mitochondrial function.This is an international collaboration project with China: one researcher comes from China and part of project will be performed in China (synthesis of precursor).

Team

Xiaoqing Zhuang, Olof Solin;Merja Haapanranta-Solin, Tove Grönroos;Juhani Knuuti

  • Head of research Markku Juntti
  • Language n/a

As of the time 14:46, March 11, 2011, Tohoku, Japan was hit by a massive earthquake. The epicentre of the earthquake was located to be undersea off the coast of Japan, and the magnitude-level was 9.0. The first earthquake also triggered a series of subsequent big earthquakes. Altogether, these earthquakes caused huge trembling on the Japanese mainland, reaching magnitude-level 7 at Kurihara City in the Miyagi prefecture, and Level 6 across many places in Tohoku. Following these huge earthquakes, those areas facing to the Pacific Ocean over the entire Tohoku area and also a northern part of Kanto areas were hit by unpredictably huge Tsunami waves of up to 40 m height. While travelling up 10 km inland, these waves caused thousands of deaths and severe damage of private and public infrastructure.

Team

Tadashi Matsumoto

  • Head of research Jari Iinatti
  • Language n/a

CoNHealth will bring together leading researchers with wide-ranging research experience in the context of a collaborative scheme of research exchanges and networking to advance current knowledge in the area of intelligent wireless networks for medical ICT applications. The project is endorsed by 8 institutions including 3 partners from EU countries (UK, Italy, and Finland), 2 partners from industrialized third countries (US and Japan), and 3 partners from an International Cooperation Partner (ICP) country (China).

Team

  • Head of research Jari Iinatti
  • Language n/a

Project focuses on a wireless body area network (WBAN) as a core of ideal ubiquitous healthcare infrastructure, which can provide us new paradigm to create innovations for future healthcare in academia and industry by employing advanced wireless technologies which Finland and Japan have been leading in a world. WBAN is a crucial wearable and implant network sensing various vital data for diagnosis and controlling actuators for health treatment around a body, and constructs a ubiquitous healthcare network combining with existing radio, and optical, networks such as a mobile cellular network and Internet. The research is divided into three paradigms: Dependable wireless communication in healthcare applications, developing the IEEE802.15.6-2012 standard, and improving the efficiency of clinical approval for compliance for novel WBAN devices.

Team

Stroke is a major cause of adult disability that poses an enormous healthcare burden. It has been estimated that in Finland annual stroke-related costs (e.g., special care, rehabilitation) are 1.1 billion euros (7 % of the annual total healthcare costs).

Team

Jukka Jolkkonen, Shen Li

Stroke is a major cause of adult disability that poses an enormous healthcare burden. It has been estimated that in Finland annual stroke-related costs (e.g., special care, rehabilitation) are 1.1 billion euros (7 % of the annual total healthcare costs).

Team

Jukka Jolkkonen, Chuansheng Zhao

Comparative legal research on climate change mitigation legislation and policy, specially energy efficiency legislation.

Team

Ari Ekroos, Sara Kymenvaara, Jenny Rontu

The ‘Exploring Tonle Sap Futures’ project (2010-13) was one of the five localised case studies of the ‘Exploring Mekong Region Futures‘ project, led by The Commonwealth Scientific and Industrial Research Organisation (CSIRO) and funded by AusAID. The Tonle Sap study looked -similarly to the entire regional project- the nexus between water, energy, food and climate change.

Team

Marko Keskinen, Matti Kummu, Aura Salmivaara, Paradis Someth, Hannu Lauri, Hans de Moel, Philip Ward, Sokhem Pech